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| Year | Brand | Card # | Description | Misc Notes |
| 2000 | Black Diamond Rookie Ed | S2 | Diamond Skills | |
| 2000 | Bowman | 2 | Regular Issue | |
| 2000 | Bowman | 2 | Retro | |
| 2000 | Bowman | E6 | Early Indicators | |
| 2000 | Bowman | MP2 | Major Power | |
| 2000 | Bowman Chrome | 2 | Regular Issue | |
| 2000 | Bowman Chrome | 29 of 50 | Rookie Reprint | |
| 2000 | Bowman Chrome | 29 of 50 | Rookie Reprint REFRACTOR | |
| 2000 | Bowman Chrome | MR4 | Meteoric Rise | |
| 2000 | Bowman Chrome | MR4 | Meteoric Rise REFRACTOR | |
| 2000 | Bowman's Best | 2 | Regular Issue | |
| 2000 | Bowman's Best | 88 | Best Performers-Reg Issue | |
| 2000 | Bowman's Best | BBS11 | Best Selections | |
| 2000 | Bowman's Best | F14 | Franchise 2000 | |
| 2000 | EX | 10 | Regular Issue | |
| 2000 | EX | 14 of 20 | E-Xplosive | 0750/2499 |
| 2000 | EX | 9 of 15 | E-Xceptional Red | 0428/1999 |
| 2000 | EX | 9 of 15 | E-Xceptional Green | 454/999 |
| 2000 | EX | 9 of 15 | E-Xceptional Blue | 228/250 |
| 2000 | Finest | 2 | Regular Issue | |
| 2000 | Finest | 2 | Refractor | |
| 2000 | Finest | 127 | Features-Reg Issue | |
| 2000 | Finest | 127 | Refractor | |
| 2000 | Finest | 138 | Gems-Reg Issue | |
| 2000 | Finest | 138 | Refractor | |
| 2000 | Finest | 275 | Counterparts | |
| 2000 | Finest | 10A | For the Record | 070/335 |
| 2000 | Finest | 10C | For the Record | 080/330 |
| 2000 | Finest | BB1 | Ballpark Bounties | |
| 2000 | Finest | DC3 | Dream Cast | |
| 2000 | Finest | FM1 | Finest Moments | |
| 2000 | Finest | FM1 | Finest Moments REF | |
| 2000 | Finest | GTD4 | Going the Distance | |
| 2000 | Fleer Focus | 118 | Regular Issue | |
| 2000 | Fleer Focus | 6 of 15 | Focal Points | |
| 2000 | Fleer Focus | 7 of 10 | Focus Pocus | |
| 2000 | Fleer Gamers | 70 | Regular Issue | |
| 2000 | Fleer Gamers | 118 | Fame Game-Regular Issue | |
| 2000 | Fleer Gamers | 2 of 15D | Determined | |
| 2000 | Fleer Gamers | 3 of 15 | Change the Game | |
| 2000 | Fleer Mystique | 87 | Regular Issue | |
| 2000 | Fleer Mystique | 2 of 10 | Supernaturals | |
| 2000 | Fleer Mystique | 8 of 10SA | Seismic Activity | |
| 2000 | Fleer Showcase | 32 | Regular Issue | |
| 2000 | Fleer Showcase | 1 of 10 | Noise of Summer | |
| 2000 | Fleer Showcase | 3 of 15 | Consummate Prose | |
| 2000 | Fleer Tradition | 2 | Reg Issue-League Leaders | |
| 2000 | Fleer Tradition | 4 | Dividends | |
| 2000 | Fleer Tradition | 8 | Ten Four | |
| 2000 | Fleer Tradition | 164 | Regular Issue | |
| 2000 | Fleer Tradition | 440 | AW-Regular Issue | |
| 2000 | Fleer Tradition | 4 of 15 | Halls Well | |
| 2000 | Fleer Tradition Glossy | 164 | Regular Issue | |
| 2000 | Fleer Tradition Glossy | 440 | AW-Regular Issue | |
| 2000 | Fleer Twizzlers | 3 of 12 | Regular Issue | |
| 2000 | Just 2K | MG.02 | Mystery Gamers GU Bat | |
| 2000 | Metal | 10 | Fusion | |
| 2000 | Metal | 24 | Regular Issue | |
| 2000 | Metal | 24 | Emerald Parallel | |
| 2000 | Metal | 10 of 10 | Hit Machines | |
| 2000 | Metal | 9 of 10 | Heavy Metal | |
| 2000 | MLB Showdown | 37 | Holofoil | |
| 2000 | MLB Showdown | NNO | Diamond Star | |
| 2000 | MLB Showdown | S18 | Percentages-Reg Issue | |
| 2000 | MLB Showdown | S2 | Regular Issue | |
| 2000 | Pacific | 2 | Ornaments | |
| 2000 | Pacific | 4 | Gold Crown Die Cuts | |
| 2000 | Pacific | 3 of 30 | 7-11 Oddball disc | |
| 2000 | Pacific | 38A | Regular Issue | |
| 2000 | Pacific | 38B | RUBY PARALLEL Batting | |
| 2000 | Pacific | 38B | Regular Issue Batting | |
| 2000 | Pacific | 38B | Copper Parallel | #11/99 |
| 2000 | Pacific Aurora | 1 | Star Factor | |
| 2000 | Pacific Aurora | 2 | Pennant Fever | |
| 2000 | Pacific Aurora | 2 | Dugout View Net-Fusions | |
| 2000 | Pacific Aurora | 3 | Scouting Reports | |
| 2000 | Pacific Aurora | 12A | Regular Issue | |
| 2000 | Pacific Aurora | 12B | Regular Issue (Striped Jersey) | |
| 2000 | Pacific Crown Collection | 1 | Timber 2000 | |
| 2000 | Pacific Crown Collection | 2 | Moment of Truth | |
| 2000 | Pacific Crown Collection | 22 | Regular Issue | |
| 2000 | Pacific Crown Collection | 29 | Checklist-Reg Issue | |
| 2000 | Pacific Crown Royale | 2 | Feature Attractions | |
| 2000 | Pacific Crown Royale | 2 | Card Supials | |
| 2000 | Pacific Crown Royale | 3 | Regular Issue | |
| 2000 | Pacific Crown Royale | 3 | Final Numbers | |
| 2000 | Pacific Crown Royale | 3 | Proof | #50/50 |
| 2000 | Pacific Crown Royale | 14 | Ruby Parallel | |
| 2000 | Pacific Invincible | 1 | Lighting the Fire | |
| 2000 | Pacific Invincible | 4 | Kings of the Diamond | |
| 2000 | Pacific Invincible | 4 | Kings of the Diamond FOIL | 263/299 |
| 2000 | Pacific Invincible | 14 | Regular Issue | |
| 2000 | Pacific Invincible | 14 | Holo Purple | 126/299 |
| 2000 | Pacific Omega | 1 | Electro-Optical | |
| 2000 | Pacific Omega | 2 | NL Contenders | |
| 2000 | Pacific Omega | 2 | Stellar Performers | |
| 2000 | Pacific Omega | 13 | Regular Issue | |
| 2000 | Pacific Omega | 20 | Full Count | |
| 2000 | Pacific Opening Day 2K | OD26 | Regular Issue | |
| 2000 | Pacific Paramount | 2 | Fielder's Choice | |
| 2000 | Pacific Paramount | 21 | Regular Issue | |
| 2000 | Pacific Paramount | 21 | Platinum Blue | 29/67 |
| 2000 | Pacific Paramount | 21 | Copper Parallel | |
| 2000 | Pacific Paramount Update | 9-U | Regular Issue | |
| 2000 | Pacific Prism | 1 | Center Stage | |
| 2000 | Pacific Prism | 1 | NL Legends | |
| 2000 | Pacific Prism | 12 | Rapture Gold | |
| 2000 | Pacific Prism | 12 | Rapture Silver | |
| 2000 | Pacific Prism | 12 | Pebble Drop Silver | |
| 2000 | Pacific Prism | 12 | Drops of Silver | |
| 2000 | Pacific Prism | 12 | Woodgrain Silver | |
| 2000 | Pacific Prism | 12 | Regular Issue | |
| 2000 | Pacific Prism | 12 | Slidders Silver | |
| 2000 | Pacific Prism | 12 | Premiere Date | #32/61 |
| 2000 | Pacific Prism | 12 | Holographic Purple | #80/99 |
| 2000 | Pacific Prism | 12 | Holographic Gold | 162/480 |
| 2000 | Pacific Prism | 12 | Holographic Blue | #11/80 |
| 2000 | Pacific Prism | 12 | Holographic Mirror | #6/160 |
| 2000 | Pacific Private Stock | 1 | Reserve | |
| 2000 | Pacific Private Stock | 2 | Extreme Action | |
| 2000 | Pacific Private Stock | 4 | PS-2000 Action | |
| 2000 | Pacific Private Stock | 10 | Regular Issue | |
| 2000 | Pacific Revolution | 1 | Triple Header | |
| 2000 | Pacific Revolution | 1 | Triple Header Platinum Blue | 345/359 |
| 2000 | Pacific Revolution | 1 | Triple Header Platinum | 522/899 |
| 2000 | Pacific Revolution | 1 | Foul Pole Net Fusion | |
| 2000 | Pacific Revolution | 4 | Season Opener | |
| 2000 | Pacific Revolution | 15 | Regular Issue | |
| 2000 | Pacific Vanguard | 1 | Diamond Architects | |
| 2000 | Pacific Vanguard | 1 | Vanguard Press | |
| 2000 | Pacific Vanguard | 1 | Cosmic Force | |
| 2000 | Pacific Vanguard | 5 | High Voltage | |
| 2000 | Pacific Vanguard | 55 | Regular Issue | |
| 2000 | Skybox | 4 | Higher Level | |
| 2000 | Skybox | 11 | E-Ticket | |
| 2000 | Skybox | 12 of 15T | The Technique | |
| 2000 | Skybox | 8 of 10SL | Skylines | |
| 2000 | Skybox | 9 of 10P | Preeminence | |
| 2000 | Skybox | 3 | Regular Issue | |
| 2000 | Skybox Dominion | 3 | Double Play | |
| 2000 | Skybox Dominion | 3 | Double Play PLUS | |
| 2000 | Skybox Dominion | 196 | Regular Issue | |
| 2000 | Skybox Dominion | 5 of 15 | Eye on October | |
| 2000 | Skybox Impact | 105 | Regular Issue | |
| 2000 | Skybox Impact | 26 of 40 | Mighty Fine in 99 | |
| 2000 | Skybox Impact | 6of10 | Point of Impact | |
| 2000 | SP Authentic | 45 | Regular Issue | |
| 2000 | SP Authentic | 87 | Buyback '99 SP Auth #7 Autograph AUTO | BGS 9.5, #234/541 |
| 2000 | SP Authentic | 93 | SP Superstars | #1088/2500 |
| 2000 | SP Authentic | PP6 | Premier Performers | |
| 2000 | SP Authentic | S4 | Supremacy | |
| 2000 | SPx | 11 | Regular Issue | |
| 2000 | SPx | F4 | Foundations | |
| 2000 | SPx | H12 | Heart of the Order | |
| 2000 | SPx | HH7 | Highlight Heroes | |
| 2000 | SPx | PB7 | Power Brokers | |
| 2000 | SPx | UT8 | Untouchable Talents | |
| 2000 | SPx | XC19 | SPXcitement | |
| 2000 | SPx | X-CJ | SPX Signatures AUTO | |
| 2000 | Stadium Club | 16 | Regular Issue | |
| 2000 | Stadium Club | 5A | Triumvirate Luminescent | |
| 2000 | Stadium Club | BB10 | Bats of Brilliance | |
| 2000 | Stadium Club | BB10 | Bats of Brilliance Die-Cut | |
| 2000 | Stadium Club | CA7 | Capture the Action | |
| 2000 | Stadium Club | SCC3 | Chrome Preview | |
| 2000 | Stadium Club | SCC3 | Chrome Preview REFRACTOR | |
| 2000 | Stadium Club Chrome | 16 | Regular Issue | |
| 2000 | Stadium Club Chrome | CS4 | Clear Shots | |
| 2000 | Stadium Club Chrome | CS4 | Clear Shots REFRACTOR | |
| 2000 | Stadium Club Chrome | TC6 | True Colors | |
| 2000 | Stadium Club Chrome | TC6 | True Colors REFRACTOR | |
| 2000 | Stadium Club Scenes | 8 | Panoramic Jumbo Card | |
| 2000 | Topps | 180 | Regular Issue | |
| 2000 | Topps | 180 | Limited Edition | |
| 2000 | Topps | OTG22 | Own The Game | |
| 2000 | Topps | OTG22 | Limited Edition | |
| 2000 | Topps | P15 | Power Players | |
| 2000 | Topps | P15 | Limited Edition | |
| 2000 | Topps | RT3 | All-Star Rookie Team | |
| 2000 | Topps | RT3 | Limited Edition | |
| 2000 | Topps | TC9 | Topps Combos | |
| 2000 | Topps | TC9 | Limited Edition | |
| 2000 | Topps Chrome | 180 | Regular Issue | |
| 2000 | Topps Chrome | AT5 | All-Topps NL Team | |
| 2000 | Topps Chrome | CK9 | Chrome Kings | |
| 2000 | Topps Chrome | OTG22 | Own The Game | |
| 2000 | Topps Chrome | P15 | Power Players | |
| 2000 | Topps Chrome | P15 | Power Players REFRACTOR | |
| 2000 | Topps Chrome | RT3 | All-Star Rookie Team | |
| 2000 | Topps Chrome | RT3 | All-Star Rookie Team REFRACTOR | |
| 2000 | Topps Chrome | TA19 | Topps Allegiance | |
| 2000 | Topps Chrome | TC9 | Topps Combos | |
| 2000 | Topps Chrome | TC9 | Topps Combos REFRACTOR | |
| 2000 | Topps Gallery | 16 | Regular Issue | |
| 2000 | Topps Gallery | 16 | Player's Private Issue | 167/250 |
| 2000 | Topps Gallery | 110 | Regular Issue | |
| 2000 | Topps Gallery | 110 | Player's Private Issue | 121/250 |
| 2000 | Topps Gallery | GE7 | Gallery Exhibits | |
| 2000 | Topps Gallery | GH2 | Gallery of Heroes | |
| 2000 | Topps Gallery | P8 | Proof Positive | |
| 2000 | Topps Gallery | TGH19 | Gallery Heritage | |
| 2000 | Topps Gold Label | 16 | Class 1 | |
| 2000 | Topps Gold Label | 16 | Class 2 | |
| 2000 | Topps Gold Label | 16 | Class 3 | |
| 2000 | Topps Gold Label | 16 | Class 3 GOLD | 019/100 |
| 2000 | Topps Gold Label | PD8 | Prospector's Dream | |
| 2000 | Topps Gold Label | T3 | The Treasury | |
| 2000 | Topps HD | 72 | Regular Issue | |
| 2000 | Topps HD | GD7 | The Game Defined | |
| 2000 | Topps Opening Day | 85 | Regular Issue | |
| 2000 | Topps Stars | 47 | Regular Issue | |
| 2000 | Topps Stars | 47 | Metallic Blue Parallel | #136/299 |
| 2000 | Topps Stars | 158 | Spotlights-Reg Issue | |
| 2000 | Topps Stars | 158 | Metallic Blue Parallel | #05/99 |
| 2000 | Topps Stars | AS9 | All Star Authority | |
| 2000 | Topps Stars | P5 | Progression | |
| 2000 | Topps Stars | WF8 | Walk of Fame | |
| 2000 | Topps Tek | 2 | Pattern 01 | |
| 2000 | Topps Tek | 2 | Pattern 02 | |
| 2000 | Topps Tek | 2 | Pattern 03 | |
| 2000 | Topps Tek | 2 | Pattern 04 | |
| 2000 | Topps Tek | 2 | Pattern 05 | |
| 2000 | Topps Tek | 2 | Pattern 06 | |
| 2000 | Topps Tek | 2 | Pattern 07 | |
| 2000 | Topps Tek | 2 | Pattern 08 | |
| 2000 | Topps Tek | 2 | Pattern 09 | |
| 2000 | Topps Tek | 2 | Pattern 10 | |
| 2000 | Topps Tek | 2 | Pattern 11 | |
| 2000 | Topps Tek | 2 | Pattern 12 | |
| 2000 | Topps Tek | 2 | Pattern 13 | |
| 2000 | Topps Tek | 2 | Pattern 14 | |
| 2000 | Topps Tek | 2 | Pattern 15 | |
| 2000 | Topps Tek | 2 | Pattern 19 GREEN | |
| 2000 | Topps Tek | 2 | GOLD Pattern #14 | #07/10 |
| 2000 | Topps Tek | 2 | GOLD Pattern #19 | #01/10 |
| 2000 | Topps Tek | A3 | Architeks | |
| 2000 | Topps Tek | DP5 | DramaTek Performers | |
| 2000 | Topps Tek | TT6 | TEKtonics | |
| 2000 | UD Black Diamond | 8 | Regular Issue | |
| 2000 | UD Black Diamond | B9 | Diamond Barrage | |
| 2000 | UD Black Diamond | CJ | A Piece of History GU BAT | |
| 2000 | UD Black Diamond | R8 | Reciprocal | |
| 2000 | UD Black Diamond | T9 | Constant Threat | |
| 2000 | UD Gold Reserve | 138 | Regular Issue | |
| 2000 | UD Gold Reserve | G10 | Solid Gold Gallery | |
| 2000 | UD Gold Reserve | K10 | 24-Karat Gems | |
| 2000 | UD Hitters Club | 8 | Regular Issue | |
| 2000 | UD Hitters Club | GE5 | Hitter's Club | |
| 2000 | UD Hitters Club | OT6 | On Target | |
| 2000 | UD HoloGrFX | 13 | Regular Issue | |
| 2000 | UD HoloGrFX | BS3 | Bomb Squad | |
| 2000 | UD HoloGrFX | SV3 | Star View | |
| 2000 | UD Ionix | 2 | Pyrotechnics | |
| 2000 | UD Ionix | 10 | Regular Issue | |
| 2000 | UD Ionix | AP5 | Awesome Powers | |
| 2000 | UD Ionix | B5 | Biorhythm | |
| 2000 | UD Ionix | R10 | Reciprocal | |
| 2000 | UD Ionix | S9 | Shockwave | |
| 2000 | UD Ionix | WZ5 | Warp Zone | |
| 2000 | UD Legends | 11 | Regular Issue | |
| 2000 | UD Legends | R9 | Reflections in Time | |
| 2000 | UD MVP | 22 | Regular Issue | |
| 2000 | UD MVP | 22 | Silver Script | |
| 2000 | UD MVP | DP4 | Drawing Power | |
| 2000 | UD MVP | DT12 | Draw Your Own Card | |
| 2000 | UD Ovation | 8 | Regular Issue | |
| 2000 | UD Ovation | 8 | ERROR w/ Jason Kendall | |
| 2000 | UD Ovation | CS9 | Center Stage Gold | |
| 2000 | UD Ovation | CS9 | Center Stage Silver | |
| 2000 | UD Ovation | CS9 | Center Stage RAINBOW | |
| 2000 | UD Ovation | LP9 | Lead Performers | |
| 2000 | UD Pros & Prospects | 48 | Regular Issue | |
| 2000 | UD Pros & Prospects | 128 | ProFame | 0041/1000 |
| 2000 | UD Pros & Prospects | B5 | Best in the Bigs | |
| 2000 | UD Victory | 48 | Regular Issue | |
| 2000 | UD Victory | 59 | Stat Leaders | |
| 2000 | UD Victory | 382 | Big Play Maker-Reg Issue | |
| 2000 | UD Victory | G2 | Glory Days | |
| 2000 | UD Vintage | M4 | Matinee Idols | |
| 2000 | Ultimate Victory | 46 | Regular Issue | |
| 2000 | Ultimate Victory | 46 | Red Parallel | 093/100 |
| 2000 | Ultimate Victory | D3 | Diamond Dignitaries | |
| 2000 | Ultimate Victory | S6 | Starstruck | |
| 2000 | Ultra | 70 | Regular Issue | |
| 2000 | Ultra | 12/15 DM | Diamond Mine | |
| 2000 | Ultra | 6 of 10 | Swing King | |
| 2000 | Ultra | 70G | Gold Medallion | |
| 2000 | Upper Deck | 314 | Regular Issue | |
| 2000 | Upper Deck | 525 | All UD Team-Reg Issue | |
| 2000 | Upper Deck | 2K10 | 2K Plus | |
| 2000 | Upper Deck | FT14 | Five Tool Talents | |
| 2000 | Upper Deck | P8 | Power Rally | |
| 2000 | Upper Deck | PP6 | Prime Performers | |
| 2000 | Upper Deck | S3 | STATitude | |
| 2000 | Upper Deck | PD3 | Pennant Driven |